Easy Stuffed Italian Meatloaf Recipe

August 15, 2025

This Easy Stuffed Italian Meatloaf is a tasty twist on the classic. It’s packed with ground meat, herbs, and gooey cheese in the middle, giving every slice a delicious surprise!

If you’re like me, the best part is when you cut into it and see that cheesy center. It’s like a little present on your plate! Perfect for family dinners or a cozy night in. 🍽️

Key Ingredients & Substitutions

Ground Beef: I like using a mix of beef and pork for extra flavor, but feel free to use all beef or even ground turkey for a lighter option.

Breadcrumbs: Italian seasoned breadcrumbs add nice flavor, but you can use plain breadcrumbs and season them yourself. Just add a pinch of Italian herbs!

Parmesan Cheese: Freshly grated is best for taste, but store-bought can work if that’s what you have. Nutritional yeast is a great vegan substitute!

Milk: You can swap it for any plant milk like almond or soy if you want a dairy-free version. Just ensure the substitute is unsweetened.

Cheese for Stuffing: Mozzarella is amazing for its meltiness. You might also try provolone or any cheese that melts well!

How Do I Properly Mix Ingredients for Meatloaf?

Mixing is crucial to the texture of your meatloaf! Too much mixing can make it tough. Here are some helpful tips:

  • Use clean hands or a fork to gently combine the ingredients until just mixed. You want everything to be distributed without overworking the meat.
  • If using your hands, try to incorporate the bread crumbs and seasonings softly, almost like folding them into the meat.
  • Avoid squeezing or kneading the mixture. It’ll give a denser texture!

Following these steps will help keep your meatloaf tender and juicy, ensuring you enjoy every cheesy bite!

Easy Stuffed Italian Meatloaf Recipe

How to Make Easy Stuffed Italian Meatloaf

Ingredients You’ll Need:

For the Meatloaf:

  • 1 ½ pounds ground beef (or a mix of beef and pork)
  • 1 cup Italian seasoned breadcrumbs
  • 1/2 cup grated Parmesan cheese
  • 1/2 cup milk
  • 2 large eggs
  • 3 cloves garlic, minced
  • 1 small onion, finely chopped
  • 2 teaspoons dried Italian seasoning (or a mix of basil, oregano, thyme)
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1 cup shredded mozzarella cheese (for stuffing)
  • 1/2 cup marinara sauce (plus extra for topping)
  • 2 tablespoons fresh parsley, chopped (optional, for garnish)

How Much Time Will You Need?

This Easy Stuffed Italian Meatloaf takes about 15 minutes to prepare, and then you’ll bake it for 60 to 70 minutes. Overall, you’ll spend about 1 hour and 15 minutes until it’s ready to serve, plus a little time for the loaf to rest after baking.

Step-by-Step Instructions:

1. Preheat the Oven:

Start by preheating your oven to 350°F (175°C). While the oven heats up, you can prepare your loaf pan by lightly greasing it or lining it with parchment paper.

2. Mix the Ingredients:

In a large bowl, combine the ground meat, breadcrumbs, Parmesan cheese, milk, eggs, minced garlic, diced onion, Italian seasoning, salt, and pepper. Use your hands or a spoon to mix everything together gently, ensuring that all the ingredients are well combined but not overworked.

3. Form the Meatloaf Layers:

Now it’s time to shape your meatloaf! Divide the mixture into two equal parts. Take the first half and press it evenly into the bottom of your loaf pan, creating a nice base.

4. Add the Cheese Filling:

Sprinkle the shredded mozzarella cheese evenly over the base layer. This is the delicious stuffed surprise inside your meatloaf!

5. Seal the Meatloaf:

Carefully take the second half of the meat mixture and spread it on top of the cheese layer, sealing the edges well so the cheese doesn’t escape during cooking.

6. Add Marinara Sauce:

Spread a layer of marinara sauce over the top of the meatloaf. This adds moisture and extra flavor!

7. Bake:

Place the loaf pan in the preheated oven and bake for 60 to 70 minutes. You’ll want to check that the internal temperature reaches 160°F (71°C) for it to be fully cooked.

8. Rest and Slice:

Once done, take your meatloaf out of the oven and let it rest for about 10 minutes. This will make slicing easier and help keep it moist.

9. Serve and Enjoy:

Slice the meatloaf into portions and garnish with chopped fresh parsley if you like. Serve it warm with sides such as mashed potatoes, roasted vegetables, or a fresh salad. Enjoy your cheesy, Italian-inspired creation!

Easy Stuffed Italian Meatloaf Recipe

FAQ About Easy Stuffed Italian Meatloaf

Can I Use Ground Turkey Instead of Beef?

Absolutely! Ground turkey is a great alternative if you’re looking for a leaner option. Just keep in mind that turkey can be drier, so you may want to add a little extra milk or a splash of olive oil to keep it moist.

Can I Prepare This Meatloaf in Advance?

Yes, you can! Prepare the meatloaf mixture and shape it in the pan, then cover and refrigerate it for up to 24 hours before baking. Just remember to add a few extra minutes to the baking time if it’s coming straight from the fridge!

How Do I Store Leftover Meatloaf?

Leftover meatloaf can be stored in an airtight container in the fridge for up to 3 days. To reheat, use the microwave or warm it gently in the oven until heated through. You might want to add a drizzle of marinara sauce to keep it moist.

What Can I Use Instead of Mozzarella Cheese?

If you don’t have mozzarella on hand, any cheese that melts well will work, such as provolone, gouda, or even cheddar for a different flavor. Just ensure it’s shredded for even melting.

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